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CRTH2 antagonists in asthma: current perspectives
Chemoattractant receptor-homologous molecule expressed on T(H)2 cells (CRTH2) binds to prostaglandin D(2). CRTH2 is expressed on various cell types including eosinophils, mast cells, and basophils. CRTH2 and prostaglandin D(2) are involved in allergic inflammation and eosinophil activation. Orally a...
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| Yayımlandı: | Clin Pharmacol |
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| Asıl Yazarlar: | , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Dove Medical Press
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5733922/ https://ncbi.nlm.nih.gov/pubmed/29276415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CPAA.S119295 |
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