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CRTH2 antagonists in asthma: current perspectives
Chemoattractant receptor-homologous molecule expressed on T(H)2 cells (CRTH2) binds to prostaglandin D(2). CRTH2 is expressed on various cell types including eosinophils, mast cells, and basophils. CRTH2 and prostaglandin D(2) are involved in allergic inflammation and eosinophil activation. Orally a...
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| Publicado no: | Clin Pharmacol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5733922/ https://ncbi.nlm.nih.gov/pubmed/29276415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CPAA.S119295 |
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