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Benzodiazepinone Derivatives as CRTH2 Antagonists
[Image: see text] Multiple CRTH2 antagonists are currently evaluated in human clinical trials for asthma and chronic obstructive pulmonary disease (COPD). During our lead optimization for CRTH2 antagonists, an observation of an intramolecular hydrogen bond in ortho-phenylsulfonamido benzophenone der...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Chemical Society
2011
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4018144/ https://ncbi.nlm.nih.gov/pubmed/24900341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml200019y |
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