Synergistic Inhibition of HCC and Liver Cancer Stem Cell Proliferation by Targeting RAS/RAF/MAPK and WNT/β-Catenin Pathways

BACKGROUND/AIM: The aim of this study is to find synergistic effect using FH535 and sorafenib by targeting the RAS/RAF/MAPK and WNT/β-catenin pathways. MATERIALS AND METHODS: 3H-Thymidine incorporation assays were performed to address Huh7 and liver cancer stem cell (LCSC) inhibition using FH535 and...

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Vydáno v:Anticancer Res
Hlavní autoři: GALUPPO, ROBERTO, MAYNARD, ERIN, SHAH, MALAY, DAILY, MICHAEL F., CHEN, CHANGGUO, SPEAR, BRETT T., GEDALY, ROBERTO
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733784/
https://ncbi.nlm.nih.gov/pubmed/24692700
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