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PKI-587 and sorafenib alone and in combination on inhibition of liver cancer stem cell proliferation
BACKGROUND: Deregulated Ras/Raf/mitogen-activated protein kinase and PI3 K/AKT/mTOR signaling pathways are significant in hepatocellular carcinoma proliferation (HCC). In this study we evaluated differences in the antiproliferative effect of dual PI3 K/Akt/mTOR and Ras/Raf/mitogen-activated protein...
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| Publicado no: | J Surg Res |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4390173/ https://ncbi.nlm.nih.gov/pubmed/23769634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2013.05.016 |
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