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AIM2 inflammasome activation and regulation: A structural perspective
Absent in melanoma 2 (AIM2) inflammasome is a multi-protein platform that recognizes aberrant cytoplasmic dsDNA and induces cytokine maturation, release and pyroptosis. It is composed of AIM2, apoptosis-associated speck-like protein containing a CARD (ASC), and caspase-1. Recent X-ray crystallograph...
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| Publicado no: | J Struct Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5733693/ https://ncbi.nlm.nih.gov/pubmed/28813641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2017.08.001 |
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