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Redox-dependent regulation of hepatocyte AIM2 inflammasome activation in sterile liver injury in mice

Sterile liver inflammation, such as liver ischemia reperfusion, hemorrhagic shock after trauma and drug-induced liver injury is initiated and regulated by endogenous mediators including DNA and reactive oxygen species. Here we identify a novel mechanism for redox-mediated regulation of AIM2-inflamma...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Sun, Qian, Loughran, Patricia, Shapiro, Richard, Shrivastava, Indira H., Antoine, Daniel J., Li, Tunliang, Yan, Zhengzheng, Fan, Jie, Billiar, Timothy R., Scott, Melanie J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5191963/
https://ncbi.nlm.nih.gov/pubmed/27774630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28893
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