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Evidence for a conserved inhibitory binding mode between the membrane fusion assembly factors Munc18 and syntaxin in animals

The membrane fusion necessary for vesicle trafficking is driven by the assembly of heterologous SNARE proteins orchestrated by the binding of Sec1/Munc18 (SM) proteins to specific syntaxin SNARE proteins. However, the precise mode of interaction between SM proteins and SNAREs is debated, as contrast...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Morey, Czuee, Kienle, C. Nickias, Klöpper, Tobias H., Burkhardt, Pawel, Fasshauer, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733584/
https://ncbi.nlm.nih.gov/pubmed/29046354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.811182
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