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Syntaxin1a variants lacking an N-peptide or bearing the LE mutation bind to Munc18a in a closed conformation
In neurons, soluble N-ethylmaleimide–sensitive factor attachment receptor (SNARE) proteins drive the fusion of synaptic vesicles to the plasma membrane through the formation of a four-helix SNARE complex. Members of the Sec1/Munc18 protein family regulate membrane fusion through interactions with th...
Tallennettuna:
| Päätekijät: | , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3732934/ https://ncbi.nlm.nih.gov/pubmed/23858467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1303753110 |
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