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Glyoxals as in vivo RNA structural probes of guanine base-pairing

Elucidation of the folded structures that RNA forms in vivo is vital to understanding its functions. Chemical reagents that modify the Watson–Crick (WC) face of unprotected nucleobases are particularly useful in structure elucidation. Dimethyl sulfate penetrates cell membranes and informs on RNA bas...

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Podrobná bibliografie
Vydáno v:RNA
Hlavní autoři: Mitchell, David, Ritchey, Laura E., Park, Hongmarn, Babitzke, Paul, Assmann, Sarah M., Bevilacqua, Philip C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733565/
https://ncbi.nlm.nih.gov/pubmed/29030489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.064014.117
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