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Glyoxals as in vivo RNA structural probes of guanine base-pairing

Elucidation of the folded structures that RNA forms in vivo is vital to understanding its functions. Chemical reagents that modify the Watson–Crick (WC) face of unprotected nucleobases are particularly useful in structure elucidation. Dimethyl sulfate penetrates cell membranes and informs on RNA bas...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Mitchell, David, Ritchey, Laura E., Park, Hongmarn, Babitzke, Paul, Assmann, Sarah M., Bevilacqua, Philip C.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733565/
https://ncbi.nlm.nih.gov/pubmed/29030489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.064014.117
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