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Functional Characterization of the Disease-Associated N-Terminal Complement Factor H Mutation W198R

Dysregulation of the complement alternative pathway is involved in the pathogenesis of several diseases, including the kidney diseases atypical hemolytic uremic syndrome (aHUS) and C3 glomerulopathy (C3G). In a patient, initially diagnosed with chronic glomerulonephritis, possibly C3G, and who 6 yea...

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Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Cserhalmi, Marcell, Uzonyi, Barbara, Merle, Nicolas S., Csuka, Dorottya, Meusburger, Edgar, Lhotta, Karl, Prohászka, Zoltán, Józsi, Mihály
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733548/
https://ncbi.nlm.nih.gov/pubmed/29321782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01800
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