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A Method for the Acute and Rapid Degradation of Endogenous Proteins

Methods for the targeted disruption of protein function have revolutionized science and greatly expedited the systematic characterization of genes. Two main approaches are currently used to disrupt protein function: DNA knockout and RNA interference, which act at the genome and mRNA level, respectiv...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell
Hauptverfasser: Clift, Dean, McEwan, William A., Labzin, Larisa I., Konieczny, Vera, Mogessie, Binyam, James, Leo C., Schuh, Melina
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cell Press 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733393/
https://ncbi.nlm.nih.gov/pubmed/29153837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.10.033
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