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Rapid and reversible knockdown of endogenous proteins by peptide-directed lysosomal degradation
Rapid and reversible methods for altering the level of endogenous proteins are critically important for studying biological systems and developing therapeutics. Here, we describe a membrane permeable targeting peptide-based method that rapidly and reversibly knocks down endogenous proteins through c...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3937121/ https://ncbi.nlm.nih.gov/pubmed/24464042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3637 |
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