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Synthesis of Novel Selenides Bearing Benzenesulfonamide Moieties as Carbonic Anhydrase I, II, IV, VII, and IX Inhibitors

[Image: see text] A series of novel selenides bearing benzenesulfonamide moieties was synthesized and investigated for the inhibition of five human (h) isoforms of zinc enzyme carbonic anhydrase (CA, EC 4.2.1.1), hCA I, II, IV, VII, and IX. These enzymes are involved in a variety of diseases, includ...

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Détails bibliographiques
Publié dans:ACS Med Chem Lett
Auteurs principaux: Angeli, Andrea, Tanini, Damiano, Capperucci, Antonella, Supuran, Claudiu T.
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2017
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733303/
https://ncbi.nlm.nih.gov/pubmed/29259736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.7b00387
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