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Synthesis of Novel Selenides Bearing Benzenesulfonamide Moieties as Carbonic Anhydrase I, II, IV, VII, and IX Inhibitors

[Image: see text] A series of novel selenides bearing benzenesulfonamide moieties was synthesized and investigated for the inhibition of five human (h) isoforms of zinc enzyme carbonic anhydrase (CA, EC 4.2.1.1), hCA I, II, IV, VII, and IX. These enzymes are involved in a variety of diseases, includ...

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Vydáno v:ACS Med Chem Lett
Hlavní autoři: Angeli, Andrea, Tanini, Damiano, Capperucci, Antonella, Supuran, Claudiu T.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2017
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733303/
https://ncbi.nlm.nih.gov/pubmed/29259736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.7b00387
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