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Radiochemical Synthesis and Evaluation of (13)N-Labeled 5-Aminolevulinic Acid for PET Imaging of Gliomas

[Image: see text] The endogenous amino acid, 5-aminolevulinic acid (5-ALA), has received significant attention as an imaging agent, including ongoing clinical trials for image-guided tumor resection due to its selective uptake and subsequent accumulation of the fluorescent protoporphyrin IX in tumor...

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Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: Pippin, Adam B., Voll, Ronald J., Li, Yuancheng, Wu, Hui, Mao, Hui, Goodman, Mark M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733259/
https://ncbi.nlm.nih.gov/pubmed/29259740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.7b00311
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