Pyrrolidine Dithiocarbamate (PDTC) Attenuates Cancer Cachexia by Affecting Muscle Atrophy and Fat Lipolysis

Cancer cachexia is a kind of whole body metabolic disorder syndrome accompanied with severe wasting of muscle and adipose tissue. NF-κB signaling plays an important role during skeletal muscle atrophy and fat lipolysis. As an inhibitor of NF-κB signaling, Pyrrolidine dithiocarbamate (PDTC) was repor...

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Dettagli Bibliografici
Pubblicato in:Front Pharmacol
Autori principali: Miao, Chunxiao, Lv, Yuanyuan, Zhang, Wanli, Chai, Xiaoping, Feng, Lixing, Fang, Yanfen, Liu, Xuan, Zhang, Xiongwen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733020/
https://ncbi.nlm.nih.gov/pubmed/29311924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00915
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