Carnosol and its analogues attenuate muscle atrophy and fat lipolysis induced by cancer cachexia

Abstract Background Cancer cachexia is a multifactorial debilitating syndrome that directly accounts for more than 20% of cancer deaths while there is no effective therapeutic approach for treatment of cancer cachexia. Carnosol (CS) is a bioactive diterpene compound present in Lamiaceae spp., which...

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Bibliografiske detaljer
Main Authors: Shanshan Lu, Yiwei Li, Qiang Shen, Wanli Zhang, Xiaofan Gu, Mingliang Ma, Yiming Li, Liuqiang Zhang, Xuan Liu, Xiongwen Zhang
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2021-06-01
Serier:Journal of Cachexia, Sarcopenia and Muscle
Fag:
Carnosol
Cancer cachexia
Muscle atrophy
Lipolysis
NF‐κB
Online adgang:https://doi.org/10.1002/jcsm.12710
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