Cancer-derived exosome miRNAs induce skeletal muscle wasting by Bcl-2-mediated apoptosis in colon cancer cachexia

Cancer cachexia is a kind of whole-body metabolic disorder syndrome accompanied by severe wasting of muscle tissue in which cancer exosomes may be involved. Analysis of clinical samples showed that the serum exosome concentrations were correlated with the development of cancer cachexia. Exosomes sec...

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Gepubliceerd in:Mol Ther Nucleic Acids
Hoofdauteurs: Miao, Chunxiao, Zhang, Wanli, Feng, Lixing, Gu, Xiaofan, Shen, Qiang, Lu, Shanshan, Fan, Meng, Li, Yiwei, Guo, Xianling, Ma, Yushui, Liu, Xuan, Wang, Hui, Zhang, Xiongwen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Gene & Cell Therapy 2021
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8141664/
https://ncbi.nlm.nih.gov/pubmed/34094711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2021.04.015
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