Murine Precision-Cut Kidney Slices as an ex vivo Model to Evaluate the Role of Transforming Growth Factor-β1 Signaling in the Onset of Renal Fibrosis

Renal fibrosis is characterized by progressive accumulation of extracellular matrix (ECM) proteins, resulting in loss of organ function and eventually requiring renal replacement therapy. Unfortunately, no efficacious treatment options are available to halt renal fibrosis and translational models to...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Stribos, Elisabeth G. D., Seelen, Marc A., van Goor, Harry, Olinga, Peter, Mutsaers, Henricus A. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732966/
https://ncbi.nlm.nih.gov/pubmed/29311960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.01026
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