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Murine Precision-Cut Kidney Slices as an ex vivo Model to Evaluate the Role of Transforming Growth Factor-β1 Signaling in the Onset of Renal Fibrosis

Renal fibrosis is characterized by progressive accumulation of extracellular matrix (ECM) proteins, resulting in loss of organ function and eventually requiring renal replacement therapy. Unfortunately, no efficacious treatment options are available to halt renal fibrosis and translational models to...

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Detalles Bibliográficos
Publicado en:Front Physiol
Main Authors: Stribos, Elisabeth G. D., Seelen, Marc A., van Goor, Harry, Olinga, Peter, Mutsaers, Henricus A. M.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732966/
https://ncbi.nlm.nih.gov/pubmed/29311960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.01026
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