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Functional studies reveal the similarities and differences between AM2 and BM2 proton channels from influenza viruses

AM2 and BM2 proton channels are attractive antiviral drug targets due to their essential roles during influenza virus replication. Although both AM2 and BM2 are proton-selective ion channels, they share little sequence similarity except for the HXXXW sequence, which suggests that their proton conduc...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Ma, Chunlong, Wang, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732874/
https://ncbi.nlm.nih.gov/pubmed/29106970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2017.10.026
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