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Structural investigation of rimantadine inhibition of the AM2-BM2 chimera channel of influenza viruses
The M2 channel of influenza A is a target of the adamantane-family antiviral drugs. Two different drug-binding sites have been reported: one inside the pore and the other is a lipid-facing pocket. A previous study showed that a chimera of M2 variants from influenza A and B that contains only the por...
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| Publicat a: | Structure |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5142205/ https://ncbi.nlm.nih.gov/pubmed/22078564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2011.09.003 |
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