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Novel piplartine-containing ruthenium complexes: synthesis, cell growth inhibition, apoptosis induction and ROS production on HCT116 cells

Piplartine (piperlongumine) is a plant-derived molecule that has been receiving intense interest due to its anticancer characteristics that target the oxidative stress. In the present paper, two novel piplartine-containing ruthenium complexes [Ru(piplartine)(dppf)(bipy)](PF(6))(2) (1) and [Ru(piplar...

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Veröffentlicht in:Oncotarget
Hauptverfasser: D’Sousa Costa, Cinara O., Araujo Neto, João H., Baliza, Ingrid R.S., Dias, Rosane B., Valverde, Ludmila de F., Vidal, Manuela T.A., Sales, Caroline B.S., Rocha, Clarissa A.G., Moreira, Diogo R.M., Soares, Milena B.P., Batista, Alzir A., Bezerra, Daniel P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732813/
https://ncbi.nlm.nih.gov/pubmed/29262647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22248
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