Novel piplartine-containing ruthenium complexes: synthesis, cell growth inhibition, apoptosis induction and ROS production on HCT116 cells

Piplartine (piperlongumine) is a plant-derived molecule that has been receiving intense interest due to its anticancer characteristics that target the oxidative stress. In the present paper, two novel piplartine-containing ruthenium complexes [Ru(piplartine)(dppf)(bipy)](PF(6))(2) (1) and [Ru(piplar...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: D’Sousa Costa, Cinara O., Araujo Neto, João H., Baliza, Ingrid R.S., Dias, Rosane B., Valverde, Ludmila de F., Vidal, Manuela T.A., Sales, Caroline B.S., Rocha, Clarissa A.G., Moreira, Diogo R.M., Soares, Milena B.P., Batista, Alzir A., Bezerra, Daniel P.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732813/
https://ncbi.nlm.nih.gov/pubmed/29262647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22248
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