ABR, a novel inducer of transcription factor C/EBPα, contributes to myeloid differentiation and is a favorable prognostic factor in acute myeloid leukemia

Active BCR related (ABR) gene deactivates ras-related C3 botulinum toxin substrate 1 (RAC1), which plays an essential role in regulating normal hematopoiesis and in leukemia. BCR gene, closely related to ABR, acts as a tumor suppressor in chronic myeloid leukemia and has overlapping functions with A...

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Опубликовано в: :Oncotarget
Главные авторы: Namasu, Carolina Yaeko, Katzerke, Christiane, Bräuer-Hartmann, Daniela, Wurm, Alexander Arthur, Gerloff, Dennis, Hartmann, Jens-Uwe, Schwind, Sebastian, Müller-Tidow, Carsten, Hilger, Nadja, Fricke, Stephan, Christopeit, Maximilian, Niederwieser, Dietger, Behre, Gerhard
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2017
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732755/
https://ncbi.nlm.nih.gov/pubmed/29262589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22093
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