Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming

Reprogramming of cellular identity using exogenous expression of transcription factors (TFs) is a powerful and exciting tool for tissue engineering, disease modeling, and regenerative medicine. However, generation of desired cell types using this approach is often plagued by inefficiency, slow conve...

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Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Ruetz, Tyson, Pfisterer, Ulrich, Di Stefano, Bruno, Ashmore, James, Beniazza, Meryam, Tian, Tian V., Kaemena, Daniel F., Tosti, Luca, Tan, Wenfang, Manning, Jonathan R., Chantzoura, Eleni, Ottosson, Daniella Rylander, Collombet, Samuel, Johnsson, Anna, Cohen, Erez, Yusa, Kosuke, Linnarsson, Sten, Graf, Thomas, Parmar, Malin, Kaji, Keisuke
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732323/
https://ncbi.nlm.nih.gov/pubmed/29174331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2017.10.013
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