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Highly efficient generation of induced neurons from human fibroblasts that survive transplantation into the adult rat brain

Induced neurons (iNs) offer a novel source of human neurons that can be explored for applications of disease modelling, diagnostics, drug screening and cell replacement therapy. Here we present a protocol for highly efficient generation of functional iNs from fetal human fibroblasts, and also demons...

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Detalhes bibliográficos
Main Authors: Pereira, Maria, Pfisterer, Ulrich, Rylander, Daniella, Torper, Olof, Lau, Shong, Lundblad, Martin, Grealish, Shane, Parmar, Malin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160709/
https://ncbi.nlm.nih.gov/pubmed/25208484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06330
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