Directly Converted Human Fibroblasts Mature to Neurons and Show Long-Term Survival in Adult Rodent Hippocampus

Direct conversion of human somatic cells to induced neurons (iNs), using lineage-specific transcription factors has opened new opportunities for cell therapy in a number of neurological diseases, including epilepsy. In most severe cases of epilepsy, seizures often originate in the hippocampus, where...

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Détails bibliographiques
Publié dans:Stem Cells Int
Auteurs principaux: Avaliani, Natalia, Pfisterer, Ulrich, Heuer, Andreas, Parmar, Malin, Kokaia, Merab, Andersson, My
Format: Artigo
Langue:Inglês
Publié: Hindawi 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727793/
https://ncbi.nlm.nih.gov/pubmed/29317869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/5718608
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