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The Properties of the Unique Age-Associated B Cell Subset Reveal a Shift in Strategy of Immune Response with Age
In aged mice, conventional naive B cells decrease and a new population of age-associated B cells (ABC)() develops. When aged unprimed mice are infected with influenza virus, there is a reduced generation of helper CD4 T cell subsets and germinal center B cells, leading to limited production of IgG A...
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| Publicado no: | Cell Immunol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5732074/ https://ncbi.nlm.nih.gov/pubmed/28712455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2017.05.009 |
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