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Aged-Related Shifts in T cell Homeostasis Lead to Intrinsic T Cell Defects
Our recent studies indicate that the longer peripheral persistence of naive CD4 T cells that occurs with age is necessary for the development of the key aging defects that lead to compromised responses to vaccination and to new pathogens or new strains of circulating infectious agents. This longer p...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3415577/ https://ncbi.nlm.nih.gov/pubmed/22564707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2012.04.001 |
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