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Mechanistic basis of cocrystal dissolution advantage

Current interest in cocrystal development resides in the advantages that the cocrystal may have in solubility and dissolution compared to the parent drug. This work provides a mechanistic analysis and comparison of the dissolution behavior of carbamazepine (CBZ) and its two cocrystals, carbamazepine...

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Détails bibliographiques
Publié dans:J Pharm Sci
Auteurs principaux: Cao, Fengjuan, Amidon, Gordon L., Rodríguez-Hornedo, Naír, Amidon, Gregory E.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732061/
https://ncbi.nlm.nih.gov/pubmed/28989017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2017.09.014
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