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Mechanistic basis of cocrystal dissolution advantage

Current interest in cocrystal development resides in the advantages that the cocrystal may have in solubility and dissolution compared to the parent drug. This work provides a mechanistic analysis and comparison of the dissolution behavior of carbamazepine (CBZ) and its two cocrystals, carbamazepine...

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Detalhes bibliográficos
Publicado no:J Pharm Sci
Main Authors: Cao, Fengjuan, Amidon, Gordon L., Rodríguez-Hornedo, Naír, Amidon, Gregory E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732061/
https://ncbi.nlm.nih.gov/pubmed/28989017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2017.09.014
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