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Mechanistic basis of cocrystal dissolution advantage

Current interest in cocrystal development resides in the advantages that the cocrystal may have in solubility and dissolution compared to the parent drug. This work provides a mechanistic analysis and comparison of the dissolution behavior of carbamazepine (CBZ) and its two cocrystals, carbamazepine...

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Dades bibliogràfiques
Publicat a:J Pharm Sci
Autors principals: Cao, Fengjuan, Amidon, Gordon L., Rodríguez-Hornedo, Naír, Amidon, Gregory E.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732061/
https://ncbi.nlm.nih.gov/pubmed/28989017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2017.09.014
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