Anti-leukemia activity of NSC-743380 in SULT1A1-expressing acute myeloid leukemia cells is associated with inhibitions of cFLIP expression and PI3K/AKT/mTOR activities

Our recent study showed that acute myeloid leukemia (AML) cells expressing SULT1A1 are highly sensitive to NSC-743380, a small molecule that inhibits STAT3 activity and induces SULT1A1-dependent apoptosis of various cancer cell lines. In this study, we characterized the molecular mechanisms of NSC-7...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Huang, Xiao, Cao, Mengru, Wu, Shuhong, Wang, Li, Hu, Jing, Mehran, Reza J., Roth, Jack A., Swisher, Stephen G., Wang, Rui-Yu, Kantarjian, Hagop M., Andreeff, Michael, Sun, Xiaoping, Fang, Bingliang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5731942/
https://ncbi.nlm.nih.gov/pubmed/29254232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22235
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados