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A non-canonical Notch complex regulates adherens junctions and vascular barrier function

The vascular barrier that separates blood from tissues is actively regulated by the endothelium and is essential for transport, inflammation, and hemostasis(1). Hemodynamic shear stress plays a critical role in maintaining endothelial barrier function(2), but how this occurs remains unknown. Here, u...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Polacheck, William J., Kutys, Matthew L., Yang, Jinling, Eyckmans, Jeroen, Wu, Yinyu, Vasavada, Hema, Hirschi, Karen K., Chen, Christopher S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5730479/
https://ncbi.nlm.nih.gov/pubmed/29160307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature24998
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