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Kindlin‐2 interacts with endothelial adherens junctions to support vascular barrier integrity

KEY POINTS: A reduction in Kindlin‐2 levels in endothelial cells compromises vascular barrier function. Kindlin‐2 is a previously unrecognized component of endothelial adherens junctions. By interacting directly and simultaneously with β‐ or γ‐catenin and cortical actin filaments, Kindlin‐2 stabiliz...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Pluskota, Elzbieta, Bledzka, Kamila M., Bialkowska, Katarzyna, Szpak, Dorota, Soloviev, Dmitry A., Jones, Sidney V., Verbovetskiy, Dmitriy, Plow, Edward F.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638888/
https://ncbi.nlm.nih.gov/pubmed/28799653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP274380
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