SmgGDS is a transient nucleolar protein that protects cells from nucleolar stress and promotes the cell cycle by regulating DREAM complex gene expression

The chaperone protein and guanine nucleotide exchange factor SmgGDS (RAP1GDS1) is a key promoter of cancer cell proliferation and tumorigenesis. SmgGDS undergoes nucleocytoplasmic shuttling, suggesting that it has both cytoplasmic and nuclear functions that promote cancer. Previous studies indicate...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Gonyo, P, Bergom, C, Brandt, A C, Tsaih, S-W, Sun, Y, Bigley, T M, Lorimer, E L, Terhune, S S, Rui, H, Flister, M J, Long, R M, Williams, C L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5730474/
https://ncbi.nlm.nih.gov/pubmed/28806394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.280
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