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Fibronectin Conformation and Assembly: Analysis of Fibronectin Deletion Mutants and Fibronectin Glomerulopathy (GFND) Mutants
To study fibronectin (FN) conformation and assembly, we generated several deletion mutants: FNΔ(I)1–5, FNΔ(III)1–3, FNΔ(III)4–8, and FNΔ(III)11–14. A monomeric form, FNmono, which lacked the C-terminal dimerization region, was also created. FNtnA–D was generated by swapping FNIII domains 1–8 in FNΔ(...
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| Опубликовано в: : | Biochemistry |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5729893/ https://ncbi.nlm.nih.gov/pubmed/28745050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00589 |
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