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Probing the Folded State of Fibronectin Type III Domains in Stretched Fibrils by Measuring Buried Cysteine Accessibility

Fibronectin (FN) is an extracellular matrix protein that is assembled into fibrils by cells during tissue morphogenesis and wound healing. FN matrix fibrils are highly elastic, but the mechanism of elasticity has been debated: it may be achieved by mechanical unfolding of FN-III domains or by a conf...

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Autors principals: Lemmon, Christopher A., Ohashi, Tomoo, Erickson, Harold P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143600/
https://ncbi.nlm.nih.gov/pubmed/21652701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.240028
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