Prevalence and characteristics of hereditary non-polyposis colorectal cancer (HNPCC) syndrome in immigrant Asian colorectal cancer patients

BACKGROUND: The prevalence of Hereditary Non-Polyposis Colorectal Cancer (HNPCC) is 2 to 5% in the Caucasian population. HNPCC is caused by genomic mutations in DNA mismatch repair genes (MMR), namely MLH1, MSH2, MSH6, PMS2, and EPCAM. A non-hereditary, acquired process of hypermethylation of the ML...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Lee, Jasmine, Xiao, Yin-Yi, Sun, Yan Yu, Balderacchi, Jasminka, Clark, Bradley, Desani, Jatin, Kumar, Vivek, Saverimuthu, Angela, Win, Khin Than, Huang, Yiwu, Xu, Yiqing
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5729240/
https://ncbi.nlm.nih.gov/pubmed/29237405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3799-y
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