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Anti-leukemic activity of bortezomib and carfilzomib on B-cell precursor ALL cell lines

Prognosis of childhood acute lymphoblastic leukemia (ALL) has been dramatically improved. However, prognosis of the cases refractory to primary therapy is still poor. Recent phase 2 study on the efficacy of combination chemotherapy with bortezomib (BTZ), a proteasome inhibitor, for refractory childh...

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Veröffentlicht in:PLoS One
Hauptverfasser: Takahashi, Kazuya, Inukai, Takeshi, Imamura, Toshihiko, Yano, Mio, Tomoyasu, Chihiro, Lucas, David M., Nemoto, Atsushi, Sato, Hiroki, Huang, Meixian, Abe, Masako, Kagami, Keiko, Shinohara, Tamao, Watanabe, Atsushi, Somazu, Shinpei, Oshiro, Hiroko, Akahane, Koshi, Goi, Kumiko, Kikuchi, Jiro, Furukawa, Yusuke, Goto, Hiroaki, Minegishi, Masayoshi, Iwamoto, Shotaro, Sugita, Kanji
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728482/
https://ncbi.nlm.nih.gov/pubmed/29236701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188680
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