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Found in translation: how preclinical research is guiding the clinical development of the BCL-2-selective inhibitor venetoclax
Since the discovery of apoptosis as a form of programmed cell death, targeting the apoptosis pathway to induce cancer cell death has been a high priority goal for cancer therapy. After decades of effort, drug discovery scientists have succeeded in generating small-molecule inhibitors of antiapoptoti...
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| Pubblicato in: | Cancer Discov |
|---|---|
| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5728441/ https://ncbi.nlm.nih.gov/pubmed/29146569 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-17-0797 |
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