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Aging alters mRNA expression of amyloid transporter genes at the blood-brain barrier
Decreased clearance of potentially toxic metabolites, due to aging changes, likely plays a significant role in the accumulation of amyloid-beta peptides (Aβ) and other macromolecules in the brains of the elderly and in Alzheimer’s disease (AD). Aging is the single most important risk factor for AD d...
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| Publicado no: | Neurobiol Aging |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5728118/ https://ncbi.nlm.nih.gov/pubmed/28654861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2017.05.011 |
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