Restoring synaptic plasticity and memory in mouse models of Alzheimer’s disease by PKR inhibition

Alzheimer’s disease (AD) is a neurodegenerative disorder associated with deficits in cognition and synaptic plasticity. While accumulation of amyloid β (Aβ) and hyper-phosphorylation of tau are parts of the etiology, AD can be caused by a large number of different genetic mutations and other unknown...

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Detalles Bibliográficos
Publicado en:Mol Brain
Main Authors: Hwang, Kyoung-Doo, Bak, Myeong Seong, Kim, Sang Jeong, Rhee, Sangmyung, Lee, Yong-Seok
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2017
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727890/
https://ncbi.nlm.nih.gov/pubmed/29233183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-017-0338-3
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