Brain-Specific SNAP-25 Deletion Leads to Elevated Extracellular Glutamate Level and Schizophrenia-Like Behavior in Mice

Several studies have associated reduced expression of synaptosomal-associated protein of 25 kDa (SNAP-25) with schizophrenia, yet little is known about its role in the illness. In this paper, a forebrain glutamatergic neuron-specific SNAP-25 knockout mouse model was constructed and studied to explor...

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Detalhes bibliográficos
Publicado no:Neural Plast
Main Authors: Yang, Hua, Zhang, Mengjie, Shi, Jiahao, Zhou, Yunhe, Wan, Zhipeng, Wang, Yicheng, Wan, Yinghan, Li, Jun, Wang, Zhugang, Fei, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727794/
https://ncbi.nlm.nih.gov/pubmed/29318050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/4526417
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