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Functional polymorphisms in asporin and CILP together with joint loading predispose to hand osteoarthritis

BACKGROUND: Osteoarthritis (OA) is the most common degenerative joint disease afflicting people in the Western world and has a strong genetic influence. The aim of this study was to examine the association of two known functional polymorphisms in the TGF-β inhibiting genes, asporin (ASPN) and cartil...

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Publicat a:BMC Genet
Autors principals: Taipale, Mari, Solovieva, Svetlana, Leino-Arjas, Päivi, Männikkö, Minna
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727665/
https://ncbi.nlm.nih.gov/pubmed/29233086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-017-0585-4
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