Common interleukin-6 promoter variants associate with the more severe forms of distal interphalangeal osteoarthritis

INTRODUCTION: The objective of this study was to investigate the relationship of the IL-6 promoter variants G-597A, G-572C and G-174C (rs1800797, rs1800796 and rs1800795, respectively), which have been shown to affect both the transcription and secretion of IL-6, to symptomatic distal interphalangea...

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Autores principales: Kämäräinen, Olli-Pekka, Solovieva, Svetlana, Vehmas, Tapio, Luoma, Katariina, Riihimäki, Hilkka, Ala-Kokko, Leena, Männikkö, Minna, Leino-Arjas, Päivi
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374458/
https://ncbi.nlm.nih.gov/pubmed/18257935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2374
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