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Functional polymorphisms in asporin and CILP together with joint loading predispose to hand osteoarthritis

BACKGROUND: Osteoarthritis (OA) is the most common degenerative joint disease afflicting people in the Western world and has a strong genetic influence. The aim of this study was to examine the association of two known functional polymorphisms in the TGF-β inhibiting genes, asporin (ASPN) and cartil...

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Vydáno v:BMC Genet
Hlavní autoři: Taipale, Mari, Solovieva, Svetlana, Leino-Arjas, Päivi, Männikkö, Minna
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727665/
https://ncbi.nlm.nih.gov/pubmed/29233086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-017-0585-4
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