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Tet1 facilitates hypoxia tolerance by stabilizing the HIF-α proteins independent of its methylcytosine dioxygenase activity
Because of the requirement of oxygen (O(2)) to produce energy, aerobic organisms developed mechanisms to protect themselves against a shortage of oxygen in both acute status and chronic status. To date, how organisms tolerate acute hypoxia and the underlying mechanisms remain largely unknown. Here,...
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Publicado no: | Nucleic Acids Res |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5727443/ https://ncbi.nlm.nih.gov/pubmed/29036334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx869 |
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