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Deletion of the fih gene encoding an inhibitor of hypoxia-inducible factors increases hypoxia tolerance in zebrafish

Many aerobic organisms have developed molecular mechanism to tolerate hypoxia, but the specifics of these mechanisms remain poorly understood. It is important to develop genetic methods that confer increased hypoxia tolerance to intensively farmed aquatic species, as these are maintained in environm...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Cai, Xiaolian, Zhang, Dawei, Wang, Jing, Liu, Xing, Ouyang, Gang, Xiao, Wuhan
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177605/
https://ncbi.nlm.nih.gov/pubmed/30126845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003004
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