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Retargeting Lentiviruses via SpyCatcher-SpyTag Chemistry for Gene Delivery into Specific Cell Types

We report a simple strategy for the creation of lentiviral vectors specific to any desired target cells. SpyTag is inserted into an engineered Sindbis virus envelope protein and displayed on the lentivirus surface to create Sindbis virus-SpyTag pseudoparticles (Sind-SpyTag-pp). The SpyTag serves as...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:mBio
Päätekijät: Kasaraneni, Nagarjun, Chamoun-Emanuelli, Ana M., Wright, Gus, Chen, Zhilei
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727413/
https://ncbi.nlm.nih.gov/pubmed/29233896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01860-17
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